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Interface Science
Interface science is a crucial component of microfabricated systems, as surface properties impact electrokinetic phenomena (such as electroosmosis and electrophoresis), surface adsorption, binding assays, and a host of other crucial issues. Our research interests in this area have included electrokinetic characterization of microfluidic substrates and laser-induced surface modifications of substrate materials.

Selected Publications and Presentations on Interface Science

Santana SM, Liu H, Bander NH, Gleghorn JP, Kirby BJ,
"Immunocapture of Prostate Cancer Cells with Anti-PSMA Antibodies in Microdevices ", , accepted, 2011.

Kirby BJ, Jodari M, Loftus M, Pratt ED, Gakhar G, Chanel-Vos C, Gleghorn JP, Santana SM, Liu H, Smith JP, Bander NH, Tagawa S, Nanus DM, Giannakakou PA,
"Functional Characterization of Circulating Tumor Cells with a Prostate-Cancer-Specific Microfluidic Device ", submitted, 2011.

Connelly JT, Kondapalli S, Parker, J Kirby BJ, Baeumner AJ
"Micro total analysis system for virus detection:microfluidic pre-concentration coupled to liposome-based detection," Analytical and Bioanalytical Chemistry, accepted, 2011.

Kondapalli S, Connelly JT, Baeumner AJ, Kirby BJ
"Integrated microfluidic preconcentrator and immunobiosensor," Microfluidics and Nanofluidics, 2011. doi

PDF version of Tandon Kirby: Ambient Pressure Effects on the Electrokinetic Potential of Zeonor-Water Interfaces

Tandon VT, Kirby BJ
"Ambient Pressure Effects on the Electrokinetic Potential of Zeonor-Water Interfaces," Journal of Colloid and Interface Science, 361:381-387, 2011. doi

Hawkins, Huang, Arasanipalai, Kirby: Automated dielectrophoretic chracterization of Mycobacterium smegmatis

Hawkins BG, Huang C, Arasanipalai S, Kirby BJ
"Automated dielectrophoretic chracterization of Mycobacterium smegmatis," Analytical Chemistry, 2011, accepted. doi

Gleghorn JP, Smith JP, Kirby BJ
"Spatial aliasing of particle displacements and collision rates in periodic asymmetric microfluidic obstacle arrays", submitted, 2011.

PDF version of Hawkins, Kirby: Electrothermal flow effects in insulating 
(electrodeless) dielectrophoresis systems

Hawkins BG, Kirby BJ
"Electrothermal flow effects in insulating (electrodeless) dielectrophoresis systems," Electrophoresis, 31:3622-3633, 2010. doi pdf

HTML version of Kirby: Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices

Kirby BJ
"Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices," Cambridge University Press, 2010.
click here for html version| Cambridge University Press

PDF version of Tandon Kirby: Transient zeta potential measuremnts in hydrophobic topas microfluidics substrates

Tandon VT, Bhagavatula S, Kirby BJ
"Transient Zeta Potential Measurements in Hydrophobic, TOPAS Microfluidic Substrates," Electrophoresis 30(15) 2656-2667, 2009. doi pdf

Hawkins BG, Tandon V, Kirby BJ
"Electrokinetic tools for cellular screening in plastic microdevices: interfacial characterization and engineering design", Meeting of the Electrochemical Society, Washington, DC, October 2007.

PDF version of Tandon V Bhagavatula SK Nelson WC Kirby BJ:
Zeta potential and electroosmotic mobility in microfluidic devices
fabricated from hydrophobic polymers: 1. The origins of charge

Tandon V, Bhagavatula SK, Nelson WC, Kirby BJ
"Zeta potential and electroosmotic mobility in microfluidic devices fabricated from hydrophobic polymers: 1. The origins of charge", Electrophoresis 29(5):1092-1101, 2008. doi pdf

PDF version of Tandon V Kirby BJ:
Zeta potential and electroosmotic mobility in microfluidic devices 
fabricated from hydrophobic polymers: 2. Slip and interfacial water structure

Tandon V, Kirby BJ
"Zeta potential and electroosmotic mobility in microfluidic devices fabricated from hydrophobic polymers: 2. Slip and interfacial water structure", Electrophoresis 29(5):1102-1114, 2008. doi pdf

PDF version of Benjamin G. Hawkins, A. Ezekial Smith, 
Yusef A. Syed, Brian J. Kirby: 
Continuous-Flow Particle Separation 
by 3D Insulative Dielectrophoresis 
Using Coherently Shaped, dc-Biased, ac Electric Fields

Hawkins BG, Smith AE, Syed YA, Kirby BJ
"Continuous-flow particle separation by 3D insulative dielectrophoresis using coherently shaped, DC-biased, AC electric fields," Analytical Chemistry, 2007. doi pdf text

PDF version of Ghosh, Bhagwat, Renshaw, Goh, Gaeta, Kirby: Low-light-level optical interactions with rubidium vapor in a photonic band-gap fiber

Ghosh S, Bhagwat AR, Renshaw CK, Goh S, Gaeta AL, Kirby BJ
"Low-light-level optical interactions with rubidium vapor in a photonic band-gap fiber," Physical Review Letters 97:023603 (2006). doi pdf arxiv

Ghosh S, Bhagwat AR, Renshaw CK, Goh S, Gaeta AL, Kirby BJ
"Coherent interactions with rubidium atoms confined in a hollow-core photonic bnad-gap fiber," APS DAMOP 2006 Annual Meeting Knoxville, TN, May 2006.

Wilkes JO , with Birmingham SG, Kirby BJ, Cheng C-Y
"Fluid Mechanics for Chemical Engineers with Microfluidics and CFD," Prentice-Hall, 2005.
click here to go to text webpage

PDF version of Mela, van den Berg, Fintschenko, Cummings, Simmons, Kirby: The zeta potential of cyclo-olefin polymer microchannels and its effects on insulative (electrodeless) dielectrophoresis particle trapping devices

Mela P, van den Berg A, Fintschenko Y, Cummings EB, Simmons BA, Kirby BJ
"The zeta potential of cyclo-olefin polymer microchannels and its effects on insulative (electrodeless) dielectrophoresis particle trapping devices," Electrophoresis 26:1792-1799 (2005). doi pdf text

PDF version of Kirby, Hasselbrink: The zeta potential of microfluidic substrates. 1. Theory, experimental techniques, and effects on separations

Kirby BJ, Hasselbrink, Jr. EF
"The Zeta Potential of Microfluidic Substrates. 1. Theory, experimental techniques, and effects on separations," Electrophoresis, 25:187-202 (2004). doi pdf text

PDF version of Kirby, Hasselbrink: The zeta potential of microfluidic substrates. 2. Data for polymers

Kirby BJ, Hasselbrink, Jr. EF
"The Zeta Potential of Microfluidic Substrates. 2. Data for polymers," Electrophoresis, 25:203-213 (2004). doi pdf text

PDF version of Reichmuth, Kirby: Effects of ammonioalkyl sulfonate internal salts on electrokinetic micropump performance and reversed-phase HPLC separations

Reichmuth DS, Kirby BJ
"Effects of Ammonioalkyl sulfonate internal salts on electrokinetic micropump performance and Reversed-Phase HPLC separations," Journal of Chromatography A, 1013:93-101 (2003). doi pdf text

PDF version of Reichmuth, Chirica, Kirby: Increasing the performance of high-pressure, high-efficiency electrokinetic micropumps using zwitterionic solute additives

Reichmuth DS, Chirica GS, Kirby BJ
"Increasing the Performance of High-Pressure, High-Efficiency Electrokinetic Micropumps Using Zwitterionic Solute Additives," Sensors and Actuators B-Chemical, 92:37-43 (2003). doi pdf text

PDF versino of Fintschenko, Kirby, Hasselbrink, Singh, Shepodd: Monolithic materials: miniature and microchip technologies

Fintschenko Y, Kirby BJ, Hasselbrink, Jr. EF, Singh AK, Shepodd TJ
"Monolithic Materials: Miniature and Microchip Technologies," in Monolithic Materials: Preparation, Properties, and Applications Elsevier, Amsterdam (2003). pdf

PDF version of Kirby, Wheeler, Zare, Fruetel, Shepodd: Programmable modification of cell adhesion and zeta potential in silica microchips

Kirby BJ, Wheeler AR, Zare RN, Fruetel JA, Shepodd TJ
"Programmable Modification of Cell Adhesion and Zeta Potential in Silica Microchips,"Lab On a Chip 3:5-10 (2003). doi pdf text

Professor Kirby's text is available at Cambridge or Amazon or Powell's or Barnes and Noble, among other vendors.