Sowmya Kondapalli

Ph.D. Student
Mechanical Engineering

Project Web Page:

Detection of viral pathogens in environmental waters

Protein refolding in microchips

Email:

sk485@cornell.edu

Address:

245 Upson Hall
Cornell University
Ithaca, NY 14853

Phone:

(607) 342-4982

Fax:

(607) 255-1222

Sowmya Kondapalli currently works on the development and evaluation of pathogen concentrators and microbiosensors for on-site environmental water sampling.

She has also worked on developing a microfluidic chip which automates combinatorial processes like protein refolding and bioconjugate synthesis.

Biography

Sowmya Kondapalli joined the Micro/Nanofluidics Laboratory in August of 2005. Sowmya completed her undergraduate degree in Mechanical Engineering from IIT Madras, India. As a part of her senior year project, she worked on building a Joule Thomson cryocooler, used for storing biological specimens, which can reach cryogenic temperatures as low as 100K.

Current Projects

Current projects include the fabrication of a nanoporous membrane in glass microchannels using in-situ photopolymerization techniques and integrating this concentration module with a microbiosensor on a single platform.

Honors and Awards

Received the award for the best  senior year project in Mechanical Engineering from IIT Madras in 2005.

Education

M.S. 2008 - Cornell University, Mechanical Engineering

B.Tech. 2005 - Indian Institute of Technology Madras, India, Mechanical Engineering

Publications and Presentations

J.T. Connelly, S. Kondapalli, B.J. Kirby, A.J. Baeumner,  "Electrochemical biosensor with integrated preconcentration module for the detection of enteric viruses", Gordon Research Conference on Bioanalytical Sensors, Colby-Sawyer College, New London, NH.

S. Kondapalli, J.T. Connelly, A.J. Baeumner, B.J. Kirby, "On-chip electrophoretic concentration of liposomes for antibody-based viral biosensors", 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) 2009, Jeju, Korea

B.G. Hawkins, C. Huang, I.S. Stranic, S. Kondapalli, B.J. Kirby, "Particle screening in polymeric microfluidic devices using insulating dielectrophoresis and frequency modulated electric fields", 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) 2009, Jeju, Korea

S. Kondapalli, J.T. Connelly, A.J. Baeumner, B.J. Kirby, "Development and evaluation of pathogen concentrators and microbiosensors for on-site environmental water sampling", Cornell Engineering Research Conference 2009, Ithaca, NY.

S. Kondapalli, B.J. Kirby, "Refolding of beta-galactosidase: Microfluidic device for reagent metering and mixing and quantification of refolding yield," Microfluidics and Nanofluidics 7(2): 275 - 281, 2009.

 S. Kondapalli, B.J. Kirby, "Refolding of beta-balactosidase in a microfluidic device", American Institute of Chemical Engineers (AIChE) Annual Meeting 2008, Philadelphia, PA.

S. Kondapalli, B.J. Kirby, "Microfluidic device for combinatorial protein refolding", 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) 2008, San Diego, CA.
 

S. Kondapalli, J.T. Connelly, A.J. Baeumner, B.J. Kirby, "On-chip electrophoretic concentration of liposomes using photopolymerized nanoporous membranes", Cornell Nanobiotechnology Center (NBTC) Annual Symposium 2008, Ithaca, NY.

B. G. Hawkins, J. P. Gleghorn, S. Kondapalli, B.J. Kirby, "Sorting, capture, and concentration of cells in microdevices: geometric design", Joint meeting of the International Society of Biorheology (ISB) and the International Society for Clinical Hemorheology (ISCH) 2008, University Park, PA.

S. Kondapalli, B.J. Kirby, "Microfluidic devices for protein refolding", PepTalk 2008, San Diego, CA.

S. Kondapalli, D.A. Putnam, B.J. Kirby, "Microfluidic device for combinatorial protein refolding", Gordon Research Conference 2007, Physics and Chemistry of Microfluidics, Waterville Valley, NH.

 S. Kondapalli, D.A. Putnam, B.J. Kirby, "Microfluidic device for combinatorial protein refolding", New York Complex Matter Workshop 2007, Cornell University, Ithaca, NY.